포스파티딜이노시톨 3,4-이중인산

3. 주요 내용

3. 1. 개념 및 정의

3. 2. 핵심 요소

3. 3. 사회적 쟁점

4. 한국 사회에 미치는 영향

4. 1. 긍정적 영향

4. 2. 부정적 영향

5. 전망과 과제

참조

_[1] 논문 Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction
_[2] 서적 Molecular Biology of the Cell Garland Science
_[3] 논문 PI(3,4)P2 Signaling in Cancer and Metabolism
_[4] 논문 The enzymatic synthesis of inositol phosphatide
_[5] 논문 Recognition of polyunsaturated acyl chains by enzymes acting on membrane lipids
_[6] 논문 Phosphoinositides: tiny lipids with giant impact on cell regulation
_[7] 간행물 Role of SHIP1 in cancer and mucosal inflammation
_[8] 간행물 Inhibitor and activator: dual functions for SHIP in immunity and cancer
_[9] 간행물 The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. evidence for conserved alternative splicing in the 4-phosphatase family
_[10] 간행물 Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling
_[11] 간행물 High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity
_[12] 간행물 PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes
_[13] 간행물 Characterization of a 3- phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
_[14] 간행물 Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
_[15] 간행물 Characterization of a 3- phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
_[16] 간행물 PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes
_[17] 간행물 PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes
_[18] 간행물 PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes
_[19] 간행물 Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling
_[20] 간행물 Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate
_[21] 간행물 The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics
_[22] 간행물 Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate
_[23] 간행물 Emerging evidence of signalling roles for PI(3,4)P2 in class I and II PI3K-regulated pathways
_[24] 간행물 Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics
_[25] 간행물 A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex
_[26] 간행물 Rac1-dependent lamellipodial motility in prostate cancer PC-3 cells revealed by optogenetic control of Rac1 activity
_[27] 논문 Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction
_[28] 서적 Molecular biology of the cell Garland science, Taylor and Francis group 2015
_[29] 논문 PI(3,4)P2 Signaling in Cancer and Metabolism https://pubmed.ncbi.[...] 2020
_[30] 논문 The enzymatic synthesis of inositol phosphatide https://pubmed.ncbi.[...] 1958-11
_[31] 논문 Recognition of polyunsaturated acyl chains by enzymes acting on membrane lipids https://pubmed.ncbi.[...] 2012-04
_[32] 논문 Phosphoinositides: tiny lipids with giant impact on cell regulation https://pubmed.ncbi.[...] 2013-07
_[33] 논문 Role of SHIP1 in cancer and mucosal inflammation https://pubmed.ncbi.[...] 2013-03
_[34] 논문 Inhibitor and activator: dual functions for SHIP in immunity and cancer https://pubmed.ncbi.[...] 2011-01
_[35] 논문 The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family https://pubmed.ncbi.[...] 1997-09-19
_[36] 논문 Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling https://pubmed.ncbi.[...] 2009-08-04
_[37] 논문 High affinity binding of inositol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on kinase activity https://pubmed.ncbi.[...] 1997-03-28
_[38] 논문 PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes https://pubmed.ncbi.[...] 2017-02-02
_[39] 논문 Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha https://pubmed.ncbi.[...] 1997-04-01
_[40] 논문 Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex https://pubmed.ncbi.[...] 2005-02-18
_[41] 논문 Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate https://pubmed.ncbi.[...] 2013-07-11
_[42] 논문 The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics https://pubmed.ncbi.[...] 2010-08-09
_[43] 논문 Emerging evidence of signalling roles for PI(3,4)P2 in Class I and II PI3K-regulated pathways https://pubmed.ncbi.[...] 2016-02
_[44] 논문 Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics https://pubmed.ncbi.[...] 2004-10
_[45] 논문 A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex https://pubmed.ncbi.[...] 2012-08-22
_[46] 논문 Rac1-dependent lamellipodial motility in prostate cancer PC-3 cells revealed by optogenetic control of Rac1 activity https://pubmed.ncbi.[...] 2014
_[47] 논문 Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction